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Development and Characterization of Treprostinil Palmitil Inhalation Aerosol for the Investigational Treatment of Pulmonary Arterial Hypertension

Treprostinil palmitil (TP) is a prodrug of treprostinil (TRE), a pulmonary vasodilator that has been previously formulated for inhaled administration via a nebulizer. TP demonstrates a sustained presence in the lungs with reduced systemic exposure and prolonged inhibition of hypoxia-induced pulmonar...

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Publicat a:Int J Mol Sci
Autors principals: Plaunt, Adam J., Islam, Sadikul, Macaluso, Tony, Gauani, Helena, Baker, Thomas, Chun, Donald, Viramontes, Veronica, Chang, Christina, Corboz, Michel R., Chapman, Richard W., Li, Zhili, Cipolla, David C., Perkins, Walter R., Malinin, Vladimir S.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7828008/
https://ncbi.nlm.nih.gov/pubmed/33430435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22020548
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