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Concise Synthesis of Functionalized Cyclobutene Analogues for Bioorthogonal Tetrazine Ligation
Novel bioorthogonal tools enable the development of new biomedical applications. Here we report the concise synthesis of a series of aryl-functionalized cyclobutene analogues using commercially available starting materials. Our study demonstrates that cyclobutene acts as a small, strained dienophile...
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| Udgivet i: | Molecules |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7827859/ https://ncbi.nlm.nih.gov/pubmed/33429851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26020276 |
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