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Precursor B-ALL Cell Lines Differentially Respond to SYK Inhibition by Entospletinib
Background: Impaired B-cell receptor (BCR) function has been associated with the progress of several B-cell malignancies. The spleen tyrosine kinase (SYK) represents a potential therapeutic target in a subset of B-cell neoplasias. In precursor B-acute lymphoblastic leukemia (B-ALL), the pathogenic r...
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| Veröffentlicht in: | Int J Mol Sci |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
MDPI
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7827334/ https://ncbi.nlm.nih.gov/pubmed/33435587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22020592 |
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