Modifications on the Tetrahydroquinoline Scaffold Targeting a Phenylalanine Cluster on GPER as Antiproliferative Compounds against Renal, Liver and Pancreatic Cancer Cells

The implementation of chemo- and bioinformatics tools is a crucial step in the design of structure-based drugs, enabling the identification of more specific and effective molecules against cancer without side effects. In this study, three new compounds were designed and synthesized with suitable abs...

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Vydáno v:Pharmaceuticals (Basel)
Hlavní autoři: Méndez-Luna, David, Morelos-Garnica, Loreley Araceli, García-Vázquez, Juan Benjamín, Bello, Martiniano, Padilla-Martínez, Itzia Irene, Fragoso-Vázquez, Manuel Jonathan, Dueñas González, Alfonso, De Pedro, Nuria, Gómez-Vidal, José Antonio, Mendoza-Figueroa, Humberto Lubriel, Correa-Basurto, José
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7826836/
https://ncbi.nlm.nih.gov/pubmed/33435260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph14010049
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