Clathrin‐mediated EGFR endocytosis as a potential therapeutic strategy for overcoming primary resistance of EGFR TKI in wild‐type EGFR non‐small cell lung cancer

OBJECTIVES: Oncogenic alterations of epidermal growth factor receptor (EGFR) signaling are frequently noted in non‐small cell lung cancer (NSCLC). In recent decades, EGFR tyrosine kinase inhibitors (TKIs) have been developed, although the therapeutic efficacy of these inhibitor is restricted to EGFR...

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Detaylı Bibliyografya
Yayımlandı:Cancer Med
Asıl Yazarlar: Kim, Boyeon, Park, Young Soo, Sung, Jae Sook, Lee, Jong Won, Lee, Saet Byeol, Kim, Yeul Hong
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2020
Konular:
Cancer Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7826488/
https://ncbi.nlm.nih.gov/pubmed/33314735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.3635
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