A phase 1 study of combined guadecitabine and cisplatin in platinum refractory germ cell cancer

PURPOSE: Germ cell tumors (GCTs) are cured with therapy based on cisplatin, although a clinically significant number of patients are refractory and die of progressive disease. Based on preclinical studies indicating that refractory testicular GCTs are hypersensitive to hypomethylating agents (HMAs),...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Cancer Med
मुख्य लेखकों: Albany, Costantine, Fazal, Zeeshan, Singh, Ratnakar, Bikorimana, Emmanuel, Adra, Nabil, Hanna, Nasser H., Einhorn, Lawrence H., Perkins, Susan M., Sandusky, George E., Christensen, Brock C., Keer, Harold, Fang, Fang, Nephew, Kenneth P., Spinella, Michael J.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: John Wiley and Sons Inc. 2020
विषय:
Clinical Cancer Research
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7826483/
https://ncbi.nlm.nih.gov/pubmed/33135391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.3583
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