An unconventional role of an ASB family protein in NF-κB activation and inflammatory response during microbial infection and colitis

Nuclear factor κB (NF-κB)–mediated signaling pathway plays a crucial role in the regulation of inflammatory process, innate and adaptive immune responses. The hyperactivation of inflammatory response causes host cell death, tissue damage, and autoinflammatory disorders, such as sepsis and inflammato...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Hou, Panpan, Jia, Penghui, Yang, Kongxiang, Li, Zibo, Tian, Tian, Lin, Yuxin, Zeng, Weijie, Xing, Fan, Chen, Yu, Li, Chunmei, Liu, Yingfang, Guo, Deyin
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2021
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7826385/
https://ncbi.nlm.nih.gov/pubmed/33431678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2015416118
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