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High-speed compressed-sensing fluorescence lifetime imaging microscopy of live cells

We present high-resolution, high-speed fluorescence lifetime imaging microscopy (FLIM) of live cells based on a compressed sensing scheme. By leveraging the compressibility of biological scenes in a specific domain, we simultaneously record the time-lapse fluorescence decay upon pulsed laser excitat...

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Bibliographische Detailangaben
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Ma, Yayao, Lee, Youngjae, Best-Popescu, Catherine, Gao, Liang
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7826382/
https://ncbi.nlm.nih.gov/pubmed/33431663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2004176118
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