Goblet cell LRRC26 regulates BK channel activation and protects against colitis in mice

Goblet cells (GCs) are specialized cells of the intestinal epithelium contributing critically to mucosal homeostasis. One of the functions of GCs is to produce and secrete MUC2, the mucin that forms the scaffold of the intestinal mucus layer coating the epithelium and separates the luminal pathogens...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Gonzalez-Perez, Vivian, Martinez-Espinosa, Pedro L., Sala-Rabanal, Monica, Bharadwaj, Nikhil, Xia, Xiao-Ming, Chen, Albert C., Alvarado, David, Gustafsson, Jenny K., Hu, Hongzhen, Ciorba, Matthew A., Lingle, Christopher J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2021
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7826367/
https://ncbi.nlm.nih.gov/pubmed/33431687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2019149118
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