Goblet cell LRRC26 regulates BK channel activation and protects against colitis in mice

Goblet cells (GCs) are specialized cells of the intestinal epithelium contributing critically to mucosal homeostasis. One of the functions of GCs is to produce and secrete MUC2, the mucin that forms the scaffold of the intestinal mucus layer coating the epithelium and separates the luminal pathogens...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Gonzalez-Perez, Vivian, Martinez-Espinosa, Pedro L., Sala-Rabanal, Monica, Bharadwaj, Nikhil, Xia, Xiao-Ming, Chen, Albert C., Alvarado, David, Gustafsson, Jenny K., Hu, Hongzhen, Ciorba, Matthew A., Lingle, Christopher J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2021
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7826367/
https://ncbi.nlm.nih.gov/pubmed/33431687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2019149118
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