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Acute skin exposure to ultraviolet light triggers neutrophil-mediated kidney inflammation

Photosensitivity to ultraviolet (UV) light affects up to ∼80% of lupus patients. Sunlight exposure can exacerbate local as well as systemic manifestations of lupus, including nephritis, by mechanisms that are poorly understood. Here, we report that acute skin exposure to UV light triggers a neutroph...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Skopelja-Gardner, Sladjana, Tai, Joyce, Sun, Xizhang, Tanaka, Lena, Kuchenbecker, James A., Snyder, Jessica M., Kubes, Paul, Mustelin, Tomas, Elkon, Keith B.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7826360/
https://ncbi.nlm.nih.gov/pubmed/33397815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2019097118
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