Quantitation of Apremilast in Beagle Dogs Plasma by UPLC-MS-MS and Its Application to Pharmacokinetic Studies

A sensitive and selective ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS-MS) method for the determination of apremilast in beagle dog plasma has been developed and successfully validated in the current study. Clopidogrel was employed as an internal standard (IS), and liqui...

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Vydáno v:J Anal Methods Chem
Hlavní autoři: Xiong, Wei, Wang, Ling, Zhang, Haiyan, Tao, Xiaoqiu, Jiang, Xuehua, Liu, Zejuan, Zhao, Jiajia, Xu, Wenwen
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2021
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7826237/
https://ncbi.nlm.nih.gov/pubmed/33510930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/8881076
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