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Genetics and Genomics of SOST: Functional Analysis of Variants and Genomic Regulation in Osteoblasts
SOST encodes the sclerostin protein, which acts as a key extracellular inhibitor of the canonical Wnt pathway in bone, playing a crucial role in skeletal development and bone homeostasis. The objective of this work was to assess the functionality of two variants previously identified (the rare varia...
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| Publicado no: | Int J Mol Sci |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7825314/ https://ncbi.nlm.nih.gov/pubmed/33419004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22020489 |
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