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Common and rare variants of WNT16, DKK1 and SOST and their relationship with bone mineral density

Numerous GWAS and candidate gene studies have highlighted the role of the Wnt pathway in bone biology. Our objective has been to study in detail the allelic architecture of three Wnt pathway genes: WNT16, DKK1 and SOST, in the context of osteoporosis. We have resequenced the coding and some regulato...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Martínez-Gil, Núria, Roca-Ayats, Neus, Monistrol-Mula, Anna, García-Giralt, Natàlia, Díez-Pérez, Adolfo, Nogués, Xavier, Mellibovsky, Leonardo, Grinberg, Daniel, Balcells, Susana
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6053384/
https://ncbi.nlm.nih.gov/pubmed/30026596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29242-8
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