Peptide Blocking CTLA-4 and B7-1 Interaction

Discovery of the B7 family immune checkpoints such as CTLA-4 (CD152), PD-1 (CD279), as well as their ligands B7-1 (CD80), B7-2 (CD86), B7-H1 (PD-L1, CD274), and B7-DC (PD-L2, CD273), has opened new possibilities for cancer immunotherapy using monoclonal antibodies (mAb). The blockade of inhibitory r...

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Dettagli Bibliografici
Pubblicato in:Molecules
Autori principali: Podlesnykh, Stepan V., Abramova, Kristina E., Gordeeva, Anastasia, Khlebnikov, Andrei I., Chapoval, Andrei I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
Soggetti:
Communication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7825301/
https://ncbi.nlm.nih.gov/pubmed/33419027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26020253
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