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Combining Model‐Based Clinical Trial Simulation, Pharmacoeconomics, and Value of Information to Optimize Trial Design
The Bayesian decision‐analytic approach to trial design uses prior distributions for treatment effects, updated with likelihoods for proposed trial data. Prior distributions for treatment effects based on previous trial results risks sample selection bias and difficulties when a proposed trial diffe...
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| Опубликовано в: : | CPT Pharmacometrics Syst Pharmacol |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
John Wiley and Sons Inc.
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7825194/ https://ncbi.nlm.nih.gov/pubmed/33314752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12579 |
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