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Identification of Small Molecules Blocking the Pseudomonas aeruginosa Type III Secretion System Protein PcrV

Pseudomonas aeruginosa is an opportunistic bacterial pathogen that employs its type III secretion system (T3SS) during the acute phase of infection to translocate cytotoxins into the host cell cytoplasm to evade the immune system. The PcrV protein is located at the tip of the T3SS, facilitates the i...

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Bibliografiske detaljer
Udgivet i:Biomolecules
Main Authors: Sundin, Charlotta, Saleeb, Michael, Spjut, Sara, Qin, Liena, Elofsson, Mikael
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7824769/
https://ncbi.nlm.nih.gov/pubmed/33406810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11010055
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