Insights into the Interaction Mechanism of DTP3 with MKK7 by Using STD-NMR and Computational Approaches

GADD45 [Formula: see text] /MKK7 complex is a non-redundant, cancer cell-restricted survival module downstream of the NF-kB survival pathway, and it has a pathogenically critical role in multiple myeloma, an incurable malignancy of plasma cells. The first-in-class GADD45 [Formula: see text] /MKK7 in...

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Vydáno v:Biomedicines
Hlavní autoři: Sandomenico, Annamaria, Di Rienzo, Lorenzo, Calvanese, Luisa, Iaccarino, Emanuela, D’Auria, Gabriella, Falcigno, Lucia, Chambery, Angela, Russo, Rosita, Franzoso, Guido, Tornatore, Laura, D’Abramo, Marco, Ruvo, Menotti, Milanetti, Edoardo, Raimondo, Domenico
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7824710/
https://ncbi.nlm.nih.gov/pubmed/33396582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9010020
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