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Expanding the Structural Diversity of DNA Methyltransferase Inhibitors

Inhibitors of DNA methyltransferases (DNMTs) are attractive compounds for epigenetic drug discovery. They are also chemical tools to understand the biochemistry of epigenetic processes. Herein, we report five distinct inhibitors of DNMT1 characterized in enzymatic inhibition assays that did not show...

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Detalhes bibliográficos
Publicado no:Pharmaceuticals (Basel)
Main Authors: Juárez-Mercado, K. Eurídice, Prieto-Martínez, Fernando D., Sánchez-Cruz, Norberto, Peña-Castillo, Andrea, Prada-Gracia, Diego, Medina-Franco, José L.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7824300/
https://ncbi.nlm.nih.gov/pubmed/33375520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph14010017
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