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Development of Anti-Virulence Therapeutics against Mono-ADP-Ribosyltransferase Toxins

Mono-ADP-ribosyltransferase toxins are often key virulence factors produced by pathogenic bacteria as tools to compromise the target host cell. These toxins are enzymes that use host cellular NAD(+) as the substrate to modify a critical macromolecule target in the host cell machinery. This post-tran...

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Publicat a:Toxins (Basel)
Autors principals: Lugo, Miguel R., Merrill, Allan R.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7824265/
https://ncbi.nlm.nih.gov/pubmed/33375750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins13010016
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