Newly Discovered and Characterized Antivirulence Compounds Inhibit Bacterial Mono-ADP-Ribosyltransferase Toxins

The mono-ADP-ribosyltransferase toxins are bacterial virulence factors that contribute to many disease states in plants, animals, and humans. These toxins function as enzymes that target various host proteins and covalently attach an ADP-ribose moiety that alters target protein function. We tested c...

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Autors principals: Turgeon, Zachari, Jørgensen, René, Visschedyk, Danielle, Edwards, Patrick R., Legree, Sarah, McGregor, Caroline, Fieldhouse, Robert J., Mangroo, Dev, Schapira, Matthieu, Merrill, A. Rod
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2011
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Mechanisms of Action: Physiological Effects
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067067/
https://ncbi.nlm.nih.gov/pubmed/21135177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01164-10
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