Newly Discovered and Characterized Antivirulence Compounds Inhibit Bacterial Mono-ADP-Ribosyltransferase Toxins

The mono-ADP-ribosyltransferase toxins are bacterial virulence factors that contribute to many disease states in plants, animals, and humans. These toxins function as enzymes that target various host proteins and covalently attach an ADP-ribose moiety that alters target protein function. We tested c...

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Detalhes bibliográficos
Main Authors: Turgeon, Zachari, Jørgensen, René, Visschedyk, Danielle, Edwards, Patrick R., Legree, Sarah, McGregor, Caroline, Fieldhouse, Robert J., Mangroo, Dev, Schapira, Matthieu, Merrill, A. Rod
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Mechanisms of Action: Physiological Effects
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067067/
https://ncbi.nlm.nih.gov/pubmed/21135177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01164-10
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