MYC DNA Methylation in Prostate Tumor Tissue is Associated with Gleason Score

Increasing evidence suggests a role of epigenetic mechanisms at chromosome 8q24, an important cancer genetic susceptibility region, in prostate cancer. We investigated whether MYC DNA methylation at 8q24 (six CpG sites from exon 3 to the 3′ UTR) in prostate tumor was associated with tumor aggressive...

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Publicado en:Genes (Basel)
Autores principales: Barry, Kathryn Hughes, Mohanty, Kareshma, Erickson, Patricia A., Wang, Difei, Shi, Jianxin, Rose, Gary, Cellini, Ashley, Clark, Kimberly, Ambulos, Nicholas, Yin, Jing, Yan, Liying, Poulin, Matthew, Meyer, Ann, Zhang, Yuji, Bentzen, Søren M., Burke, Allen, Hussain, Arif, Berndt, Sonja I.
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7823928/
https://ncbi.nlm.nih.gov/pubmed/33374332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes12010012
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