MYC DNA Methylation in Prostate Tumor Tissue is Associated with Gleason Score

Increasing evidence suggests a role of epigenetic mechanisms at chromosome 8q24, an important cancer genetic susceptibility region, in prostate cancer. We investigated whether MYC DNA methylation at 8q24 (six CpG sites from exon 3 to the 3′ UTR) in prostate tumor was associated with tumor aggressive...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: Barry, Kathryn Hughes, Mohanty, Kareshma, Erickson, Patricia A., Wang, Difei, Shi, Jianxin, Rose, Gary, Cellini, Ashley, Clark, Kimberly, Ambulos, Nicholas, Yin, Jing, Yan, Liying, Poulin, Matthew, Meyer, Ann, Zhang, Yuji, Bentzen, Søren M., Burke, Allen, Hussain, Arif, Berndt, Sonja I.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7823928/
https://ncbi.nlm.nih.gov/pubmed/33374332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes12010012
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