Apolipoprotein E deficiency induces a progressive increase in tissue iron contents with age in mice

Association of both iron/hepcidin and apolipoprotein E (ApoE) with development of Alzheimer disease (AD) and atherosclerosis led us to hypothesize that ApoE might be required for body iron homeostasis. Here, we demonstrated that ApoE knock-out (KO) induced a progressive accumulation of iron with age...

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Vydáno v:Redox Biol
Hlavní autoři: Ma, Juan, Qian, Christopher, Bao, Yong, Liu, Meng-Yue, Ma, Hui-Min, Shen, Meng-Qi, Li, Wei, Wang, Jiao-Jiao, Bao, Yu-Xin, Liu, Yong, Ke, Ya, Qian, Zhong-Ming
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2021
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7823209/
https://ncbi.nlm.nih.gov/pubmed/33493903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2021.101865
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