Protease-Activated Receptor-2 Deficiency Attenuates Atherosclerotic Lesion Progression and Instability in Apolipoprotein E-Deficient Mice

Inflammatory mechanisms are involved in the process of atherosclerotic plaque formation and rupture. Accumulating evidence suggests that protease-activated receptor (PAR)-2 contributes to the pathophysiology of chronic inflammation on the vasculature. To directly examine the role of PAR-2 in atheros...

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Publicat a:Front Pharmacol
Autors principals: Zuo, Pengfei, Zuo, Zhi, Zheng, Yueyue, Wang, Xin, Zhou, Qianxing, Chen, Long, Ma, Genshan
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5603739/
https://ncbi.nlm.nih.gov/pubmed/28959204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00647
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