Shikonin inhibits proliferation of melanoma cells by MAPK pathway-mediated induction of apoptosis

Shikonin, a natural product isolated from the roots of Lithospermum erythrorhizon, exhibits pharmacological effects against inflammation, ulcers, infections, and tumors. In the present study, we aimed to investigate the antitumor effects of shikonin on the human melanoma cell line, A375SM, and in an...

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Podrobná bibliografie
Vydáno v:Biosci Rep
Hlavní autoři: Lee, Jae Han, Han, So Hee, Kim, You Min, Kim, Sung Hyun, Yoo, Eun Seon, Woo, Joong Seok, Jung, Gi Hwan, Jung, Soo Hyun, Kim, Bum Seok, Jung, Ji Youn
Médium: Artigo
Jazyk:Inglês
Vydáno: Portland Press Ltd. 2021
Témata:
Cancer
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7823184/
https://ncbi.nlm.nih.gov/pubmed/33403388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20203834
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