Induction of Apoptosis by Fucoidan in Human Leukemia U937 Cells through Activation of p38 MAPK and Modulation of Bcl-2 Family

The present study investigated possible mechanisms on the apoptosis induction of human leukemic cells by fucoidan, a sulfated polysaccharide found in marine algae. Fucoidan treatment of cells resulted in inhibition of growth and induction of apoptosis, as measured by 3-(4,5-dimetylthiazol-2-yl)-2,5-...

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Autores principales: Park, Hyun Soo, Hwang, Hye Jin, Kim, Gi-Young, Cha, Hee-Jae, Kim, Wun-Jae, Kim, Nam Deuk, Yoo, Young Hyun, Choi, Yung Hyun
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3736427/
https://ncbi.nlm.nih.gov/pubmed/23880928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md11072347
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