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Profiling serum antibodies with a pan allergen phage library identifies key wheat allergy epitopes

Allergic reactions occur when IgE molecules become crosslinked by antigens such as food proteins. Here we create the ‘AllerScan’ programmable phage display system to characterize the binding specificities of anti-allergen IgG and IgE antibodies in serum against thousands of allergenic proteins from...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Monaco, Daniel R., Sie, Brandon M., Nirschl, Thomas R., Knight, Audrey C., Sampson, Hugh A., Nowak-Wegrzyn, Anna, Wood, Robert A., Hamilton, Robert G., Frischmeyer-Guerrerio, Pamela A., Larman, H. Benjamin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7822912/
https://ncbi.nlm.nih.gov/pubmed/33483508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20622-1
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