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Gene Editing Targeting the DUX4 Polyadenylation Signal: A Therapy for FSHD?
Facioscapulohumeral dystrophy (FSHD, OMIM: 158900, 158901) is the most common dystrophy in adults and so far, there is no treatment. Different loci of the disease have been characterized and they all lead to the aberrant expression of the DUX4 protein, which impairs the function of the muscle, ultim...
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| Publicado no: | J Pers Med |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7822190/ https://ncbi.nlm.nih.gov/pubmed/33374516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jpm11010007 |
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