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(p)ppGpp-Dependent Regulation of the Nucleotide Hydrolase PpnN Confers Complement Resistance in Salmonella enterica Serovar Typhimurium

The stringent response is an essential mechanism of metabolic reprogramming during environmental stress that is mediated by the nucleotide alarmones guanosine tetraphosphate and pentaphosphate [(p)ppGpp]. In addition to physiological adaptations, (p)ppGpp also regulates virulence programs in pathoge...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Chau, N. Y Elizabeth, Pérez-Morales, Deyanira, Elhenawy, Wael, Bustamante, Víctor H., Zhang, Yong E., Coombes, Brian K.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7822145/
https://ncbi.nlm.nih.gov/pubmed/33139383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00639-20
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