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(p)ppGpp-Dependent Regulation of the Nucleotide Hydrolase PpnN Confers Complement Resistance in Salmonella enterica Serovar Typhimurium

The stringent response is an essential mechanism of metabolic reprogramming during environmental stress that is mediated by the nucleotide alarmones guanosine tetraphosphate and pentaphosphate [(p)ppGpp]. In addition to physiological adaptations, (p)ppGpp also regulates virulence programs in pathoge...

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Dettagli Bibliografici
Pubblicato in:Infect Immun
Autori principali: Chau, N. Y Elizabeth, Pérez-Morales, Deyanira, Elhenawy, Wael, Bustamante, Víctor H., Zhang, Yong E., Coombes, Brian K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7822145/
https://ncbi.nlm.nih.gov/pubmed/33139383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00639-20
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