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Timing of proteasome inhibition as a pharmacologic strategy for prevention of muscle contractures in neonatal brachial plexus injury

Neonatal brachial plexus injury (NBPI) causes disabling and incurable contractures, or limb stiffness, which result from proteasome‐mediated protein degradation impairing the longitudinal growth of neonatally denervated muscles. We recently showed in a mouse model that the 20S proteasome inhibitor,...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Goh, Qingnian, Nikolaou, Sia, Shay‐Winkler, Kritton, Emmert, Marianne E., Cornwall, Roger
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7821701/
https://ncbi.nlm.nih.gov/pubmed/33236396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.202002194
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