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Timing of proteasome inhibition as a pharmacologic strategy for prevention of muscle contractures in neonatal brachial plexus injury

Neonatal brachial plexus injury (NBPI) causes disabling and incurable contractures, or limb stiffness, which result from proteasome‐mediated protein degradation impairing the longitudinal growth of neonatally denervated muscles. We recently showed in a mouse model that the 20S proteasome inhibitor,...

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Bibliografische gegevens
Gepubliceerd in:FASEB J
Hoofdauteurs: Goh, Qingnian, Nikolaou, Sia, Shay‐Winkler, Kritton, Emmert, Marianne E., Cornwall, Roger
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7821701/
https://ncbi.nlm.nih.gov/pubmed/33236396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.202002194
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