Timing of proteasome inhibition as a pharmacologic strategy for prevention of muscle contractures in neonatal brachial plexus injury

Neonatal brachial plexus injury (NBPI) causes disabling and incurable contractures, or limb stiffness, which result from proteasome‐mediated protein degradation impairing the longitudinal growth of neonatally denervated muscles. We recently showed in a mouse model that the 20S proteasome inhibitor,...

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Bibliographic Details
Published in:FASEB J
Main Authors: Goh, Qingnian, Nikolaou, Sia, Shay‐Winkler, Kritton, Emmert, Marianne E., Cornwall, Roger
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2020
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7821701/
https://ncbi.nlm.nih.gov/pubmed/33236396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.202002194
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