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Overview of Biologically Active Nucleoside Phosphonates

The use of the phosphonate motif featuring a carbon-phosphorous bond as bioisosteric replacement of the labile P–O bond is widely recognized as an attractive structural concept in different areas of medicinal chemistry, since it addresses the very fundamental principles of enzymatic stability and mi...

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Detalhes bibliográficos
Publicado no:Front Chem
Main Authors: Groaz, Elisabetta, De Jonghe, Steven
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7821050/
https://ncbi.nlm.nih.gov/pubmed/33490040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2020.616863
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