The biological process of lysine‐tRNA charging is therapeutically targetable in liver cancer

BACKGROUND & AIMS: Mature transfer RNAs (tRNA) charged with amino acids decode mRNA to synthesize proteins. Dysregulation of translational machineries has a fundamental impact on cancer biology. This study aims to map the tRNAome landscape in liver cancer patients and to explore potential therap...

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Detalles Bibliográficos
Publicado en:Liver Int
Main Authors: Zhang, Ruyi, Noordam, Lisanne, Ou, Xumin, Ma, Buyun, Li, Yunlong, Das, Pronay, Shi, Shaojun, Liu, Jiaye, Wang, Ling, Li, Pengfei, Verstegen, Monique M. A., Reddy, D. Srinivasa, van der Laan, Luc J. W., Peppelenbosch, Maikel P., Kwekkeboom, Jaap, Smits, Ron, Pan, Qiuwei
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2020
Assuntos:
Experimental Hepatology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7820958/
https://ncbi.nlm.nih.gov/pubmed/33084231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/liv.14692
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