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Facile Stereoselective Reduction of Prochiral Ketones by using an F(420)‐dependent Alcohol Dehydrogenase

Effective procedures for the synthesis of optically pure alcohols are highly valuable. A commonly employed method involves the biocatalytic reduction of prochiral ketones. This is typically achieved by using nicotinamide cofactor‐dependent reductases. In this work, we demonstrate that a rather unexp...

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Pubblicato in:Chembiochem
Autori principali: Martin, Caterina, Tjallinks, Gwen, Trajkovic, Milos, Fraaije, Marco W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7820951/
https://ncbi.nlm.nih.gov/pubmed/32935896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.202000651
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