C4b Binding Protein Acts as an Innate Immune Effector Against Influenza A Virus

C4b Binding Protein (C4BP) is a major fluid phase inhibitor of the classical and lectin pathways of the complement system. Complement inhibition is achieved by binding to and restricting the role of activated complement component C4b. C4BP functions as a co-factor for factor I in proteolytic inactiv...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Varghese, Praveen M., Murugaiah, Valarmathy, Beirag, Nazar, Temperton, Nigel, Khan, Haseeb A., Alrokayan, Salman H., Al-Ahdal, Mohammed N., Nal, Beatrice, Al-Mohanna, Futwan A., Sim, Robert B., Kishore, Uday
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7820937/
https://ncbi.nlm.nih.gov/pubmed/33488586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.585361
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