Complement-Independent Modulation of Influenza A Virus Infection by Factor H

The complement system is an ancient innate immune defense mechanism that can recognize molecular patterns on the invading pathogens. Factor H, as an inhibitor of the alternative pathway, down-regulates complement activation on the host cell surface. Locally synthesized factor H at the site of infect...

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Detalhes bibliográficos
Main Authors: Valarmathy Murugaiah, Praveen M. Varghese, Soad M. Saleh, Anthony G. Tsolaki, Salman H. Alrokayan, Haseeb A. Khan, Kate S. Collison, Robert B. Sim, Béatrice Nal, Futwan A. Al-Mohanna, Uday Kishore
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020-03-01
Colecção:Frontiers in Immunology
Assuntos:
innate immunity
complement
factor H
vaccinia virus complement control protein
influenza A virus
pseudotyped lentiviral particles
Acesso em linha:https://www.frontiersin.org/article/10.3389/fimmu.2020.00355/full
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