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Failure to recombine is a common feature of human oogenesis

Failure of homologous chromosomes to recombine is arguably the most important cause of human meiotic nondisjunction, having been linked to numerous autosomal and sex chromosome trisomies of maternal origin. However, almost all information on these “exchangeless” homologs has come from genetic mappin...

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Détails bibliographiques
Publié dans:Am J Hum Genet
Auteurs principaux: Hassold, Terry, Maylor-Hagen, Heather, Wood, Anna, Gruhn, Jennifer, Hoffmann, Eva, Broman, Karl W., Hunt, Patricia
Format: Artigo
Langue:Inglês
Publié: Elsevier 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7820622/
https://ncbi.nlm.nih.gov/pubmed/33306948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2020.11.010
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