PD-L1 overexpression in EBV-positive gastric cancer is caused by unique genomic or epigenomic mechanisms

Epstein-Barr virus-positive gastric cancer [EBV (+) GC] is a distinct GC subtype with unique genetic and epigenetic aberrations. Here, we examined resected GC samples and publicly available microarray data and The Cancer Genome Atlas (TCGA) database to identify the mechanism underlying overexpressio...

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Udgivet i:Sci Rep
Main Authors: Nakano, Hiroshi, Saito, Motonobu, Nakajima, Shotaro, Saito, Katsuharu, Nakayama, Yuko, Kase, Koji, Yamada, Leo, Kanke, Yasuyuki, Hanayama, Hiroyuki, Onozawa, Hisashi, Okayama, Hirokazu, Fujita, Shotaro, Sakamoto, Wataru, Saze, Zenichiro, Momma, Tomoyuki, Mimura, Kosaku, Ohki, Shinji, Goto, Akiteru, Kono, Koji
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7820576/
https://ncbi.nlm.nih.gov/pubmed/33479394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-81667-w
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