PD-L1 overexpression in EBV-positive gastric cancer is caused by unique genomic or epigenomic mechanisms

Epstein-Barr virus-positive gastric cancer [EBV (+) GC] is a distinct GC subtype with unique genetic and epigenetic aberrations. Here, we examined resected GC samples and publicly available microarray data and The Cancer Genome Atlas (TCGA) database to identify the mechanism underlying overexpressio...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Nakano, Hiroshi, Saito, Motonobu, Nakajima, Shotaro, Saito, Katsuharu, Nakayama, Yuko, Kase, Koji, Yamada, Leo, Kanke, Yasuyuki, Hanayama, Hiroyuki, Onozawa, Hisashi, Okayama, Hirokazu, Fujita, Shotaro, Sakamoto, Wataru, Saze, Zenichiro, Momma, Tomoyuki, Mimura, Kosaku, Ohki, Shinji, Goto, Akiteru, Kono, Koji
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7820576/
https://ncbi.nlm.nih.gov/pubmed/33479394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-81667-w
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