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Myomerger promotes fusion pore by elastic coupling between proximal membrane leaflets and hemifusion diaphragm

Myomerger is a muscle-specific membrane protein involved in formation of multinucleated muscle cells by mediating the transition from the early hemifusion stage to complete fusion. Here, we considered the physical mechanism of the Myomerger action based on the hypothesis that Myomerger shifts the sp...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Golani, Gonen, Leikina, Evgenia, Melikov, Kamran, Whitlock, Jarred M., Gamage, Dilani G., Luoma-Overstreet, Gracia, Millay, Douglas P., Kozlov, Michael M., Chernomordik, Leonid V.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7820291/
https://ncbi.nlm.nih.gov/pubmed/33479215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20804-x
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