Myomaker and Myomerger work independently to control distinct steps of membrane remodeling during myoblast fusion

Classic mechanisms for membrane fusion involve transmembrane proteins that assemble into complexes and dynamically alter their conformation to bend membranes, leading to mixing of membrane lipids (hemifusion) and fusion pore formation. Myomaker and Myomerger govern myoblast fusion and muscle formati...

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Gepubliceerd in:Dev Cell
Hoofdauteurs: Leikina, Evgenia, Gamage, Dilani G., Prasad, Vikram, Goykhberg, Joanna, Crowe, Michael, Diao, Jiajie, Kozlov, Michael M., Chernomordik, Leonid V., Millay, Douglas P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6203449/
https://ncbi.nlm.nih.gov/pubmed/30197239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2018.08.006
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