A nuclear protein, PfMORC confers melatonin dependent synchrony of the human malaria parasite P. falciparum in the asexual stage

The host hormone melatonin is known to modulate the asexual cell-cycle of the human malaria parasite Plasmodium falciparum and the kinase PfPK7 is fundamental in the downstream signaling pathways. The nuclear protein PfMORC displays a histidine kinase domain and is involved in parasite cell cycle co...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Singh, Maneesh K., Tessarin-Almeida, Giulliana, Dias, Barbara K. M., Pereira, Pedro Scarpellli, Costa, Fahyme, Przyborski, Jude M., Garcia, Celia R. S.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2021
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7820235/
https://ncbi.nlm.nih.gov/pubmed/33479315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-81235-2
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