The negative feedback loop of NF-κB/miR-376b/NFKBIZ in septic acute kidney injury

Sepsis is the leading cause of acute kidney injury (AKI). However, the pathogenesis of septic AKI remains largely unclear. Here, we demonstrate a significant decrease of microRNA-376b (miR-376b) in renal tubular cells in mice with septic AKI. Urinary miR-376b in these mice was also dramatically decr...

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Publicado en:JCI Insight
Autores principales: Liu, Zhiwen, Tang, Chengyuan, He, Liyu, Yang, Danyi, Cai, Juan, Zhu, Jiefu, Shu, Shaoqun, Liu, Yuxue, Yin, Lijun, Chen, Guochun, Liu, Yu, Zhang, Dongshan, Dong, Zheng
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2020
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7819752/
https://ncbi.nlm.nih.gov/pubmed/33328388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.142272
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