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Differences in the alveolar macrophage toponome in humanized SP-A1 and SP-A2 transgenic mice

Alveolar macrophages (AMs) are differentially regulated by human surfactant protein-A1 (SP-A1) or SP-A2. However, AMs are very heterogeneous and differences are difficult to characterize in intact cells. Using the Toponome Imaging System (TIS), an imaging technique that uses sequential immunostainin...

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Pubblicato in:JCI Insight
Autori principali: Phelps, David S., Chinchilli, Vernon M., Weisz, Judith, Yang, Lili, Shearer, Debra, Zhang, Xuesheng, Floros, Joanna
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7819750/
https://ncbi.nlm.nih.gov/pubmed/33141765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.141410
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