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Sex differences in the acute in vivo effects of different human SP-A variants on the mouse alveolar macrophage proteome

Surfactant protein A (SP-A) is involved in lung innate immunity. Humans have two SP-A genes, SFTPA1 and SFTPA2, each with several variants. We examined the in vivo effects of treatment with specific SP-A variants on the alveolar macrophage (AM) proteome from SP-A knockout (KO) mice. KO mice received...

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Bibliographic Details
Main Authors: Phelps, David S., Umstead, Todd M., Floros, Joanna
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128237/
https://ncbi.nlm.nih.gov/pubmed/24954098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jprot.2014.06.007
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