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Base-Pair Mismatch Can Destabilize Small DNA Loops through Cooperative Kinking
Base-pair mismatch can relieve mechanical stress in highly strained DNA molecules, but how it affects their kinetic stability is not known. Using single-molecule fluorescence resonance energy transfer, we measured the lifetimes of tightly bent DNA loops with and without base-pair mismatch. Surprisin...
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| Yayımlandı: | Phys Rev Lett |
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| Asıl Yazarlar: | , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2019
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7819736/ https://ncbi.nlm.nih.gov/pubmed/31283336 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1103/PhysRevLett.122.218101 |
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