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All‐trans retinoic acid induces leukemia resistance to NK cell cytotoxicity by down‐regulating B7‐H6 expression via c‐Myc signaling

BACKGROUND: The interaction between activating receptor NKp30 and its major tumor ligand B7‐H6 is important for NK cell‐mediated tumor rejection. However, the regulation of B7‐H6 by tumor therapeutics remains largely unknown. In this study, we investigated the regulation of B7‐H6 by all‐trans retino...

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Vydáno v:Cancer Commun (Lond)
Hlavní autoři: Cao, Guoshuai, Cheng, Ying, Zheng, Xiaodong, Wei, Haiming, Tian, Zhigang, Sun, Rui, Sun, Haoyu
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7819554/
https://ncbi.nlm.nih.gov/pubmed/34236140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cac2.12121
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