Differential effects of chronic immunosuppression on behavioral, epigenetic, and Alzheimer’s disease-associated markers in 3xTg-AD mice

BACKGROUND: Circulating autoantibodies and sex-dependent discrepancy in prevalence are unexplained phenomena of Alzheimer’s disease (AD). Using the 3xTg-AD mouse model, we reported that adult males show early manifestations of systemic autoimmunity, increased emotional reactivity, enhanced expressio...

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Detalhes bibliográficos
Publicado no:Alzheimers Res Ther
Main Authors: Kapadia, Minesh, Mian, M. Firoz, Ma, Donglai, Hutton, Craig P., Azam, Amber, Narkaj, Klotilda, Cao, Chuanhai, Brown, Breanna, Michalski, Bernadeta, Morgan, David, Forsythe, Paul, Zovkic, Iva B., Fahnestock, Margaret, Sakic, Boris
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7818784/
https://ncbi.nlm.nih.gov/pubmed/33472690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-020-00745-9
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